| 1552
B.C. |
Earliest
documentation of diabetes on the 3rd Dynasty
Egyptian papyrus by physician Hesy-Ra |
| 1st
Century A.D. |
Diabetes
explained as "the melting down of flesh and
limbs into urine," by Arateus. |
| 16th
Century |
Paracelsus
calls diabetes as a serious ailment. |
|
|
| 1870s |
French
physician, Bouchardat, notices the disappearance of glycosuria
in diabetic patients in Paris. |
|
|
| 19th
Century |
Czech
scientist, I.V. Pavlov, discovers the links between the
nervous system and gastric secretion. |
|
|
| 1900-1915 |
"Fad"
diabetic diets include: the "oat-cure" (of oatmeal),
the milk diet, the rice cure, and "potato therapy". |
|
|
| 1908 |
German
scientist, Georg Zuelzer prepares the first injectible
pancreatic extract to repress glycosuria. |
|
|
| 1910-1920 |
Frederick
Madison Allen and Elliot P. Joslin show up as the diabetes
specialists in the U.S. |
|
|
| 1913 |
F.M.
Allen publishes the book, Studies Concerning Glycosuria and
Diabetes, a book which is significant for the revolution in
diabetes therapy that developed from it. |
|
|
| 1919 |
F.M.
Allen publishes Total Dietary Regulation in the Treatment of
Diabetes. |
|
|
| July
1, 1920 |
Dr.
Banting opens his first office in Ontario where his first
patient comes on July 29th. His total income for his first
month amount to $4.00. |
|
|
| 1922 |
Dr.
Collip's insulin extracts first tested in Toronto on a human
being, a 14-year-old boy named Leonard Thompson. |
|
|
| 1922 |
James
Havens becomes the first American effectively treated with
insulin. |
|
|
| 1922 |
Eli
Lilly and Company and the University of Toronto enter a deal
for the bulk production of insulin. |
|
|
| 1923 |
Dr.
Banting and Prof. Macleod are awarded the Nobel Prize in
Physiology or Medicine. |
|
|
| 1940s |
Connection
established between diabetes and kidney and eye diseases. |
|
|
| 1944 |
Standard
insulin syringe is prepared. |
|
|
| 1946 |
Dr.
Best co-founds a diabetes alliance under the name Diabetic
Association of Ontario. |
|
|
| 1955 |
Oral
drugs are developed to help lower blood glucose levels. |
|
|
| 1959 |
Two
major categories of diabetes are documented: type-1
(insulin-dependent) diabetes and type-2
(non-insulin-dependent) diabetes. |
|
|
| 1970 |
Blood
glucose meters and insulin pumps are developed. |
|
|
| 1983 |
First
biosynthetic human insulin debuts. |
|
|
| 1986 |
Insulin
pen delivery system is developed. |
|
|
| 1996 |
75th
Anniversary of the discovery of insulin commemorated
worldwide. |
|
|
| 1998 |
The
United Kingdom Prospective Diabetes Study (UKPDS) is
published. |
|
|
| 1999 |
Guidelines
for the Nutritional Management of Diabetes is published. |
