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SUGAR CHEMISTRY
& METABOLISM
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Sugars,
a major form of carbohydrates, are found probably in all green
plants. There are three main simple sugars -sucrose, fructose,
and glucose. Sucrose is a amalgamation of fructose and glucose
and the body quickly breaks it down into simple sugars.
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This
all-inclusive review of the fundamental biochemical and
physiological processes concerned in the digestion and
metabolism of sugars emphasizes that the source of sugars in
foods does not, in itself, affect the rate of absorption or the
metabolism of sugars. Nevertheless, the forms in which sugars
are ingested, and the physical and chemical properties of food,
do affect the rates of absorption.
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Monosaccharides
such as glucose and fructose have a low molecular weight.
Consequently, they cross the mucosal cell membranes in the small
intestine by simple diffusion. Glucose, the major CnH2nOn
species entering the mucosal enterocyte, is absorbed via a
carrier-mediated co-transporter system. This transporter system
is sodium dependent and research shows that feeding
carbohydrate-rich diets can induce it.
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Disaccharides
like sucrose and lactose are too bulky to cross over the mucosal
membrane and have to be hydrolyzed prior to absorption. Sucrose
is somewhat effortlessly hydrolyzed in weak acidic conditions at
ambient temperatures. Disacchardases as sucrases, lactases etc
in the margin membranes of the intestinal mucosal break down
sucrose and lactose to monosaccharides.
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The
absorption rate of sugars is dependent on the form in which they
are ingested, the collective effects of individual food patterns
on gastric emptying and the physical properties of the
intestinal contents. Gastric emptying is influenced by a number
of factors- soluble components of a meal are emptied from the
stomach before the insoluble components; the greater the volume
of stomach contents, the slower the rate of emptying.
Osmolarity plays an important role - high solute concentrations
delay emptying; low gastric pH & fat emulsions inhibit
emptying. As soon as sugars have been absorbed, their transport
and metabolism is analogous and the dietary source differences
cease to affect.
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-NEXT-
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Know
more about
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Monosaccharides
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Disaccharides
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Starches
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Glycogen
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Cellulose
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